An ascending single and multiple dose study of the safety, tolerability, pharmacokinetics and antitumor activity of once-daily oral treatment with EO1001 – a novel irreversible pan-ErbB inhibitor with promising brain penetration – in patients with advanced cancer

An ascending single and multiple dose study of the safety, tolerability, pharmacokinetics and antitumor activity of once-daily oral treatment with EO1001 – a novel irreversible pan-ErbB inhibitor with promising brain penetration – in patients with advanced cancer

Helen Wheeler, Jeffrey Bacha, Sarath Kanekal, Ian Nisbet, Harry Pedersen, Neil Sankar, Wang Shen, Kathy Skoff, Wang Zhen Zhong, Dennis M. Brown

American Association of Cancer Research Annual Meeting.  June 2020, Virtual Conference Event.

EO1001: A first-in-class irreversible pan-ErbB inhibitor with excellent brain penetration

EO1001: A first-in-class irreversible pan-ErbB inhibitor with excellent brain penetration

Wang Shen, Jeffrey Bacha, Sarath Kanekal, Neil Sankar, Wang Zhen Zhong, Yasuyuki Yoshida, Tomoko Ozawa, Tsun-Wen Yao, Andrew T. Parsa, Jeffrey J. Raizer, Shi-Yuan Cheng, Alexander H. Stegh, Andrew P. Mazar, Francis J. Giles, Harry D. Pedersen, Jann N. Sarkaria, Nicholas Butowski, Theodore Nicolaides, C. David James, and Dennis Brown

American Association of Cancer Research / International Association for the Study of Lung Cancer Joint Meeting.  January 2020, San Diego, USA

Preclinical development of EO1001, a novel irreversible brain penetrating pan-ErbB inhibitor (Oral Presentation)

Preclinical development of EO1001, a novel irreversible brain penetrating pan-ErbB inhibitor (Oral Presentation)

Wang Shen, Jeffrey Bacha, Sarath Kanekal, Neil Sankar, Wang ZhenZhong, Yasuyuki Yoshida, Tomoko Ozawa, Tsun-Wen Yao, Andrew T. Parsa, Jeffrey J. Raizer, Shi-Yuan Cheng, Alexander H. Stegh, Andrew P. Mazar, Francis J. Giles, Harry D. Pedersen, Jann N. Sarkaria, Nicholas Butowski, Theodore Nicolaides, C. David James, and Dennis Brown

Society for NeuroOncology Inaugural Conference on Brain Metastases.  August 2019,  New York, USA

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